A Novel System for the Quantification of the ADCC Activity of Therapeutic Antibodies
نویسندگان
چکیده
منابع مشابه
A Novel System for the Quantification of the ADCC Activity of Therapeutic Antibodies
Novel ADCC effector cells expressing the V-variant or F-variant of FcγRIIIa (CD16a) and firefly luciferase under the control of a chimeric promoter incorporating recognition sequences for the principal transcription factors involved in FcγRIIIa signal transduction, together with novel target cells overexpressing a constant high level of the specific antigen recognized by rituximab, trastuzumab,...
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ژورنال
عنوان ژورنال: Journal of Immunology Research
سال: 2017
ISSN: 2314-8861,2314-7156
DOI: 10.1155/2017/3908289